---
title: Neural Circuit Mechanisms of Emotion and Motivation
description: When there are perturbations in the neural circuits mediating reward processing, fear, motivation, memory or inhibitory control, we may observe a number of disease states such as substance abuse, attention-deficit disorder, anxiety and depression.
---

![NNR-Neural-Circuit-990x200.png](https://go.technologynetworks.com/hs-fs/hubfs/NNR-Neural-Circuit-990x200.png?width=990&name=NNR-Neural-Circuit-990x200.png "NNR-Neural-Circuit-990x200.png")

# Overview

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# Webinar Summary

Behaviors are motivated by two emotional valences: Seeking pleasure and avoiding pain. Although most animals are capable of learning to assign either positive or negative associations to environmental cues, we are only beginning to understand the underlying neural circuits and the plasticity that mediates the formation, revision or extinction of an associative memory.

 In this webinar, Dr. Kay Tye will review the experimental details of her group’s work examining the synaptic plasticity, neural dynamics and technological approaches they apply to investigate the neural circuit mechanisms of emotion and motivation.

 By attending this webinar, you will learn about the tools and approaches used by the Tye group in their experiments, including:

- Optogenetic approaches
- In vivo electrophysiology with optogenetic-mediated photoidentification or “phototagging”
- Use of viral vectors for targeting genetically-encodable proteins.

# Speaker Information:

![Dr. Kay Tye](https://go.technologynetworks.com/hs-fs/hubfs/Technology%20Networks/Landing%20Pages/TN%20Webinars/Neuroscience%20Webinar/Dr.KayTye.png?width=170&height=150&name=Dr.KayTye.png "Dr. Kay Tye")

Dr. Kay Tye  
Assistant Professor, Dept. of Brain & Cognitive Sciences   
Picower Institute for Learning and Memory, Massachusetts Institute of Technology

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