Polybrominated flame retardants, such as polybrominated diphenyl ethers (PBDEs), are persistent organic compounds that are found in the environment and in the food chain. Biomonitoring data show that PBDE concentrations have increased in recent years in humans and in wildlife. Humans are exposed to PBDEs mainly through ingestion of contaminated food and breathing contaminated air. Since PBDEs are potentially linked to a wide range of adverse health effects in humans, such as endocrine disruption, neurodevelopmental toxicity, and cancer, there is increasing public health concern about these compounds.
The webinar will discuss the use of Thermo Scientific™ Exactive™ GC Orbitrap™ GC-MS mass spectrometer for the analysis of PBDEs in environmental samples. It will also discuss the challenges that laboratories face in terms of selectivity and sensitivity in complex sample matrices, increasing sample throughput, and reducing the cost per sample. The webinar will also explore how Orbitrap GC-MS can achieve:
Ultratrace quantification of PBDEs in environmental samples (at low ppt levels) levels using Exactive GC Orbitrap technology.
Rapid sample throughput with full separation of 27 native PBDEs in <11 minutes.
Robust determination of PBDEs in complex matrices using electron ionization rather than soft ionization techniques such as negative chemical ionization.
Key Learning Objectives:
Learn about orbitrap GC-MS and how it can be used to selectively analyze PBDEs in environmental samples with confidence at low ppt levels in routine analyses
How to achieve full separation of 27 native PDBEs in food in under 11 minutes using the new TG-PBDE column
Learn how to automate data processing and reporting using a Chromeleon chromatography data system with isotope dilution quantification for PBDE analysis
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