Small changes in Post Translational Modifications (PTMs) can have a huge impact on Critical Quality Attributes (CQAs) and a biotherapeutic’s potential clinical success. Creating an efficient PTM workflow represents a significant challenge to biopharmaceutical development - so faster routes to optimizing process and control strategies will always be beneficial.
In this webinar, Dan Kristensen, Ph.D., will explain how his team has overcome the hurdles of creating quantitative PTM workflows, from sample prep to data analysis, using novel software tools and he will demonstrate best practices for determining quantitative LC/MS data for CQAs.
Attend this webinar to:
Learn how visualization of the data is essential to obtain intuitive insight into what was measured by the mass spectrometer
Impact of novel software tools that radically change and improve biopharmaceutical development
How to ensure desired product quality
How to improve quantitative peptide mapping
How to analyse complex disulfide bonds
How to best determine glycosylation
How to overcome complex analytical and reporting challenges
Dan Bach Kristensen, Ph.D Principal Scientist, Symphogen
Eric Carlson, Ph.D CEO and President, Protein Metrics