Preparing Perfect Non-Covalent Protein Complexes for Analysis by Mass Spectrometry: 12 Key Thoughts to Keep in Mind

[How to Guide]

Preparing, purifying, analysing and identifying the constituent components of non-covalently-interacting protein complexes by mass spectrometry has become significantly simpler and easier over the last two decades. However there are still many points that are easily overlooked in the successful preparation and analysis of these complexes.

Download this guide to learn:

  • Tips and tricks for performing and optimizing protein-protein interactomics
  • How to avoid common contamination issues
  • Samples that may assist with downstream troubleshooting


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