4D-Lipidomics™: Searching for the Fountain of Youth
To confidently characterize complex lipidomes of whole organisms, researchers require comprehensive MS/MS coverage of detected lipids.
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General Summary
To confidently characterize complex lipidomes of whole organisms, researchers require comprehensive MS/MS coverage of detected lipids. Compared to conventional analyses, the timsTOF Pro, used with Parallel Accumulation Serial Fragmentation (PASEF) acquisition mode, acquires MS/MS spectra with uncompromised sensitivity and resolution.
This webinar will demonstrate Bruker’s fully integrated lipidomics workflow in MetaboScape and outline how novel 4D-lipidomics tools has been used to gain a better understanding of how a sphingolipid mutation in the C. elegans relates to an increased lifespan – or in other words, the fountain of youth.
Attend the webinars to discover how to:
- Increase confidence in lipid annotation using rule-based annotation to reduce false positives
- Increase the number of MS/MS in a single run to allow for a higher level of chain composition annotation
- Automatically record reproducible CCS for all lipids within a sample to further add confidence
- See how new visualisation tools, including Kendrick mass defect plots, can save time and simplify your research
Speaker Information:
Scientist
Research Unit Analytical BioGeoChemistry, Helmholtz Zentrum München
Software Engineer
Bruker Daltonik GmbH
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