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APP NOTE

Automated Method Development for Pharmaceuticals

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The number of applications for supercritical fluid chromatography (SFC) is constantly growing. This is mainly due to the unique separation characteristics of SFC, which facilitate separation of a broad range of compounds with high efficiency.

Almost all achiral stationary phases known in liquid chromatography (LC) can be used in SFC, offering a broad selectivity. However, due to the compressibility of the mobile phase and the retention mechanism in SFC, method development can be a challenging task.

Download this application note to find out more about:

  • Read how six different pharmaceutical active compounds were separated and detected by SFC/time-of-flight mass spectrometry.
  • Discover the benefits of software-assisted method development in achiral SFC.
  • Learn how ChemStation Method Scouting Wizard software significantly reduces the time necessary to create screening procedures.