Disruptions to carefully orchestrated cell signaling pathways can lead to pathological states. In cancer, genetic mutations or epigenetic alterations to genes regulating signaling pathways can promote malignant transformation by triggering various pathological mechanisms. These mechanisms circumvent the cell’s normal checks and balances.
Download this listicle to learn how aberrant cell signaling can impact:
- Proliferation/metabolism
- Cell cycle/DNA repair/apoptosis
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Angiogenesis
