Pyruvate Kinase Inhibitor Measurements and Effortless Data Analysis Using the MARS Data Analysis Software
Pyruvate kinase is an enzyme involved in energy-supplying glycolysis and ATP synthesis, thus is pivotal for the eucaryotic energy metabolism. In addition, overexpression of pyruvate kinase is believed to play a role in cancer.
Elevated levels of the PKM2 isoform of pyruvate kinase can be used as a cancer marker and are associated with unfavorable prognosis. Accordingly, the development of pyruvate kinase inhibitors may offer new treatments for various cancers.
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