---
title: Get a High-Resolution View of Your Lipid Nanoparticles
description: "Download this app note to discover:\nConfident LNP component confirmation using HRAM MS and MS/MS data\nConfident identification of low abundant lipid impurities and degradants at <0.1% in LNP formulations\nSimultaneous lipid quantification and unknown metabolite identification with LOD of 0.1ng/mL in complex biological matrices"
image: https://go.technologynetworks.com/hubfs/Technology%20Networks/Landing%20Pages/Thermo/Kris/September%202021/Untitled-2.png
---

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App Note

# Get a High-Resolution View of Your Lipid Nanoparticles

![TechNet Landing Pages March App Note Image 300x400 (BioTech Campaign) (004)-1](https://go.technologynetworks.com/hs-fs/hubfs/TechNet%20Landing%20Pages%20March%20App%20Note%20Image%20300x400%20(BioTech%20Campaign)%20(004)-1.png?width=250&name=TechNet%20Landing%20Pages%20March%20App%20Note%20Image%20300x400%20(BioTech%20Campaign)%20(004)-1.png)Lipid nanoparticles (LNP) play a key role in effectively protecting and transporting mRNA to target cells in mRNA-based vaccines and therapeutics. To ensure the quality and safety of LNP, lipid components and associated impurities/degradants need to be carefully characterized in raw materials and formulation. The lipids and their metabolites need to be identified and quantified to understand their distribution, clearance and biodegradation pathways in the body.

**Download this app note to discover:**

- Confident LNP component confirmation using HRAM MS and MS/MS data
- Confident identification of low abundant lipid impurities and degradants at <0.1% in LNP formulations
- Simultaneous lipid quantification and unknown metabolite identification with LOD of 0.1ng/mL in complex biological matrices

**Brought to you by:**

 

**![Thermo Fisher](https://go.technologynetworks.com/hs-fs/hubfs/Images/TS/emails/2017%20Innovations/Thermo%20Fisher.png?width=182&name=Thermo%20Fisher.png)**

 

**Download this app note to discover**:

- Confident LNP component confirmation using HRAM MS and MS/MS data
- Confident identification of low abundant lipid impurities and degradants at <0.1% in LNP formulations
- Simultaneous lipid quantification and unknown metabolite identification with LOD of 0.1ng/mL in complex biological matrices

Access this App Note for FREE Now!

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