The dynamic and flexible nature of biomolecules poses a major challenge for structural biologists. Thus, the full characterization of a macromolecular system requires the combination of many structure-determination techniques, an approach known as integrative structural biology.
In this context, advances in mass spectrometry (MS) techniques in combination with cryo-electron microscopy (cryo-EM) and other structural tools is revolutionizing the understanding of protein structure, function and dynamics.
Download this eBook to learn more about:
• Tools for integrative structural biology
• Combining cryo-EM, cryo-ET and mass spectrometry
• The benefits of integrated modeling