Illuminating the Role of the Adaptive Immune Response in Neurodegeneration

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The role of the adaptive immune system in neurodegenerative diseases, such as Alzheimer’s, is controversial. Although neuroinflammation is thought to drive the pathology of age-related neurodegenerative diseases, a comprehensive understanding requires additional insights, including clarity into which T cell clones are expanded in the disease state and the antigens to which they are responding.

Download this research snapshot to discover:

  • • How the immune repertoire changes in patients with age-related neurodegeneration
  • • How adaptive immune cells are involved in these neurodegenerative diseases
  • • An approach to studying key immune changes in neurodegeneration at single cell resolution