---
title: Improve Recovery of Critical Protein Samples
description: "Download this app note to learn more about how to select the best filter membrane that:\n\nAvoids product loss\nEnsures reliable results \nPerforms consistently over a wide range of conditions "
image: https://go.technologynetworks.com/hubfs/Technology%20Networks/Landing%20Pages/Sartorius/SQL%20Campaign/Lab%20Filtration/smartmockups_knt158u5.png
---

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APP NOTE

# Improve Recovery of Critical Protein Samples

![smartmockups_knt158u5](https://go.technologynetworks.com/hs-fs/hubfs/Technology%20Networks/Landing%20Pages/Sartorius/SQL%20Campaign/Lab%20Filtration/smartmockups_knt158u5.png?width=500&name=smartmockups_knt158u5.png "smartmockups_knt158u5")

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![smartmockups_knt158u5](https://go.technologynetworks.com/hs-fs/hubfs/Technology%20Networks/Landing%20Pages/Sartorius/SQL%20Campaign/Lab%20Filtration/smartmockups_knt158u5.png?width=450&height=349&name=smartmockups_knt158u5.png "smartmockups_knt158u5")

Protein loss during sample preparation can be an obstacle to reliable product quantitation in all biopharmaceutical settings. Samples are often prepared from feedstocks containing insoluble particles and therefore require a solid-liquid separation before analysis to protect analytical instruments. Because separation by centrifugation requires a difference in density between solid and liquid phase, sample filtration can be advantageous and membrane filters offer absolute particle retention. However, filter membranes can adsorb analytes like proteins and thereby distort the results of the subsequent analyses.

**Download this app note to learn how to select the best filter membrane to:**

- Avoid product loss
- Ensure reliable results 
- Achieve consistency across a range of conditions

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