Increased Throughput and Coverage for the Annotation of Saponins Using a Structure-Based MS Approach

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Saponins are major components of Chinese medicine. They can reduce the side effects of radiotherapy and chemotherapy and they have been shown to exert anticancer and cardiovascular protective activities. Despite possessing numerous advantageous pharmacological properties, the comprehensive annotation of saponins remains challenging because of the limited availability of authentic standards and the structural diversity of the compound.

Download this app note to discover how a structure-based mass spectrometry workflow can be used to:

  • Increase the numbers of annotated saponin compounds within a limited library 
  • Annotate the saponin class compounds that contain the basic saponin structures
  • Collect more structurally relevant fragment ion information