App Note

Kinetic Curvature: Assessment of Small Molecule Kinetics and Affinity

Kinetic Curvature: Assessment of Small Molecule Kinetics and Affinity Using OneStep® Injections in SPR Screening

The detection and characterization of binding events is facilitated by sensitive biophysical technologies. Surface plasmon resonance (SPR) is a core technology used in many pharma and biotechnology settings for this purpose, however traditional initial SPR screening of weak affinity compounds using a single fixed concentration injection can present numerous challenges.

Download this app note to discover how OneStep® injections can help you:

  • Avoid solubility limitations
  • Increase hit confidence and shorten timelines
  • Gather richer datasets for more comprehensive analysis


Download this app note to discover how OneStep® injections can help you:

  • Avoid solubility limitations
  • Increase hit confidence and shorten timelines
  • Gather richer datasets for more comprehensive analysis

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