Ligand-Receptor Binding Kinetics on the PHERAstar® Microplate Reader
Drugs are characterized by their equilibrium constant KD, which describes the affinity of the compound to its target. However, this dissociation constant only applies to the equilibrium state and neglects the importance of the speed of association and dissociation.
The optimal kinetic binding of a drug differs with the target of interest and related disease. Therefore, it is important to have reliable methods for determining speeds of association and dissociation.
In this app note, discover a method for analyzing binding kinetics that is:
