Microglia are the resident immune cells of the central nervous system and play significant roles in the regulation of homeostasis and the management of tissue response to inflammatory or pathological insults. Microglia impact synaptic remodeling and turnover of dendritic spines through the removal of damaged or unnecessary neurons or synapses however limited tools and in vitro model systems exist to enable optimizing, monitoring and analyzing functional and morphological changes of these cells.
Download this poster to learn about an approach that can be used to:
- Characterize morphology
- Quantify functional phagocytic activity
- Quantify efferocytic activity