---
title: "Micro Scale Separation: A Chromatography System for Low Volume Size Exclusion Chromatography"
description: "Download this app note to learn more about the recent advances in cryo-EM including:\n\nNear-atomic resolution of protein structures\nRequiring significantly less protein samples vs crystallography\nMuch faster time-to-results and higher sample throughput"
image: https://go.technologynetworks.com/hubfs/Technology%20Networks/Landing%20Pages/BIO-RAD/November%202021/smartmockups_kw2enqni.jpg
---

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App Note 

# Microscale Separation: A Chromatography System for Low Volume Size Exclusion Chromatography

The structural characterization of complex proteins gives researchers a glimpse into their *in vivo* mechanistic functions and complex chemistries. In the case of drug development, structural information of proteins involved in disease pathways is crucial for downstream rational design of novel therapeutics.

The field of structural biology is currently undergoing a renaissance due to significant advances in cryogenic electron microscopy (cryo-EM) following the emergence of direct electron detectors and advanced computational platforms.

**Download this app note to learn more about the recent advances in cryo-EM including:**

- Near-atomic resolution of protein structures
- Requiring significantly less protein samples vs crystallography
- Much faster time-to-results and higher sample throughput

**Brought to you by:**

 

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**Download this app note to learn more about the recent advances in cryo-EM including:**

- Near-atomic resolution of protein structures
- Requiring significantly less protein samples vs crystallography
- Much faster time-to-results and higher sample throughput

Download this App Note for FREE Now!

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