Multicellular Tissue Models and Methods to Identify Tool Compounds for Interrogation of Novel Targets

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Despite great progress in our understanding of central nervous system (CNS) structure and function, discovery of novel efficacious therapeutics has been challenging. It is increasingly recognized that CNS dysfunction involves complex interactions amongst multiple cell types, which has driven the development of multicellular tissue models and other models to enable further investigation. Whilst multicellular tissue models can facilitate target validation for novel targets, there are not always suitable tool compounds available to extensively investigate the biology.

Watch this webinar to learn more about:

  • • Tractable models that better recapitulate complex cell-to-cell interactions
  • • A novel biophysical fragment based library that can identify novel inhibitors and modulators of CNS targets
  • • Delivery of lead-like compounds for neuroscience drug discovery projects