In medicine, gene therapy is the process where nucleic acids are delivered to a patient’s cells as a therapeutic drug to treat an array of genetic diseases. All gene therapies utilize either viral or non-viral vectors to deliver the DNA or RNA into the host cell. Viral vectors infect the host cell to introduce the genetic material and are more efficient at transfecting the host cell compared to non-viral vectors like cationic lipids or chemical carriers. However, they can have immunogenic side effects depending on the specific virus used. Therefore, the choice of appropriate viral vector is a critical component when developing the drug.
Download this eBook to learn more about:
- Analysis and characterization of adeno-associated virus (AAV) proteins for gene therapy
- Simple western analysis of AAV proteins for cell and gene therapy
- Characterizing CAR T Cell therapy biomarkers through multianalyte analysis