Generating Gapless, Telomere-to-Telomere Plant Genome Assemblies

Now Available On-Demand

Reconstructing plant genomes is a difficult task due to their unusual ploidy, the large number of repetitive elements present and they are often large in size. Sequencing technologies that are capable of producing long reads, such as Oxford Nanopore’s, show promise for obtaining more complete and accurate genome assemblies. The first critical step here is the extraction of high-molecular weight DNA using the appropriate protocol. In the case of homozygous genomes, this technology can generate contigs that represent complete chromosomes and reveal the architecture of complex regions, like centromeres, rDNA clusters, or clusters of paralogous genes.

In this presentation, Caroline will focus on the sequencing of a banana genome, and the reconstruction of complete chromosomes from telomere to telomere using nanopore sequencing technology.

Attend this webinar to learn more about:
  • Generating gapless, telomere-to-telomere plant genome assemblies with nanopore technology
  • Using long and ultra-long nanopore reads to resolve highly repetitive sequences

Speaker Information:


Caroline Belser

Genoscope, CEA



Attend this webinar to explore:

  • The importance of developing a diverse set of human reference genomes
  • Computational methods for assembling high-quality genomes using long-read sequencing data
  • Computational methods for mapping annotations onto new reference genomes

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