---
title: Pre-Clinical Quantification of Trastuzumab in Rat Plasma
description: "Download this app note to learn how immunoaffinity-high resolution accurate mass assay:\n\nHas increased selectivity and sensitivity\nDisplays excellent robustness, reproducibility and dynamic range\nEnables the confirmation of both in vitro and in vivo peptide modifications"
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---

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App Note

# Preclinical Quantification of Trastuzumab in Rat Plasma

In quantifying therapeutic peptides and proteins in biological matrices, traditional ELISA-only based techniques can suffer from high variability, narrow dynamic range, problems with selectivity and typically cannot use internal standards.

Download this app note to learn how immunoaffinity-high resolution accurate mass assay:

- Has increased selectivity and sensitivity
- Displays excellent robustness, reproducibility and dynamic range
- Enables the confirmation of both *in vitro* and *in vivo* peptide modifications

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Download this app note to learn how immunoaffinity-high resolution accurate mass assay:

- Has increased selectivity and sensitivity
- Displays excellent robustness, reproducibility and dynamic range
- Enables the confirmation of both in vitro and in vivo peptide modifications

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