A Rapid Method to Quantitatively Screen Bispecific Antibody using Protein A and His1K Biosensors


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Bispecific antibodies (bsAbs) are capable of binding to two different antigens, and thus present unique opportunities to the pharmaceutical industry.

Functional evaluation of bsAbs during pharmaceutical development is critical to their success, but this is not without challenges. Existing evaluative methods such as ELISA and SPR are commonly used but are often time consuming.

Therefore, there is high demand for a rapid, simple method for the functional assessment of two or more interactions of bispecific therapeutics.

In this app note, discover an assay that caters to this demand, with a method that is:

  • Versatile
  • High-throughput
  • Low-cost