Melting temperature (Tm) gives an accurate indication of the base composition in a sample with Tm often used as a QC check by manufacturers and researchers.
Thermal melt experiments are typically performed by UV-Vis spectrophotometry. Traditionally, to ensure accurate and reproducible data, a very slow temperature ramp rate is required meaning that experiments take a long time.
To overcome this issue, the Agilent Cary 3500 Multizone UV-Vis spectrophotometer uses integrated in-cuvette temperature probes.
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