--- title: Rapid Phosphoproteomics With Dia-PASEF description: "Download this app note to discover a platform that can:\n\nIdentify more than 12,500 phosphopeptides from low input material without the need for a project-specific library\nDetect more than 9,300 phosphopeptides, including co-eluted position isomers, in short 7-minute gradients\nProduce results with a high degree of reproducibility and data completeness" image: https://go.technologynetworks.com/hubfs/Technology%20Networks/Landing%20Pages/Bruker/2023/Jan/Bruker%20Thumbnail%20PASEF.png --- ![BlueTwoLine](https://go.technologynetworks.com/hubfs/Technology%20Networks/Logos/BlueTwoLine.png "BlueTwoLine") ![TN_Stacked_White](https://go.technologynetworks.com/hubfs/Technology%20Networks/Logos/TN_Stacked_White.png "TN_Stacked_White") ![TN_Stacked_White-1](https://go.technologynetworks.com/hubfs/Imported%20images/TN_Stacked_White-1.png "TN_Stacked_White-1") App Note # Rapid Phosphoproteomics With DIA-PASEF Posttranslational modifications (PTMs) are covalent processing events that change the properties of a protein by addition of a modifying group to one or more of its amino acids. Due to its prominent role in cellular signaling, protein phosphorylation is one of the most studied PTMs. Mass spectrometry-based phosphoproteomics now routinely measures tens of thousands of phosphorylation sites on a proteome-wide scale. Increasing the throughput and sensitivity of phosphoproteomics approaches is highly desirable to disentangle their functional relevance. **Download this app note to discover a platform that can:** - Identify more than 12,500 phosphopeptides from low input material without the need for a project-specific library - Detect more than 9,300 phosphopeptides, including co-eluted position isomers, in short 7-minute gradients - Produce results with a high degree of reproducibility and data completeness **Brought to you by:**   **![Bruker Logo](https://go.technologynetworks.com/hs-fs/hubfs/Technology%20Networks/TN%20Sales%20and%20Marketing/2021%20-%20OS,%20Webinar,%20Event%20Promo/Proteomics%20June%202021%20OS/Bruker%20Logo.png?width=231&name=Bruker%20Logo.png)**   **Download this app note to discover a platform that can:** - Identify more than 12,500 phosphopeptides from low input material without the need for a project-specific library - Detect more than 9,300 phosphopeptides, including co-eluted position isomers, in short 7-minute gradients - Produce results with a high degree of reproducibility and data completeness Download this App Note for FREE Now! 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