The ability to characterize and monitor the product quality attributes (PQA) of a biotherapeutic is paramount for scientists. The traditional workflow involves collision induced dissociation (CID)-based MS/MS for identification of PQAs, followed by MS/MS workflows for quantification.However, this means that separate experiments are required to achieve quantification of selected species.
The multi-attribute method (MAM) is a powerful LC-MS method that overcomes this challenge by simultaneously monitoring and quantifying multiple PQAs in a single injection.
- Differentiate isomers that are challenging for traditional methods
- Streamline your data flow
- Gain confidence in your results with compliance-ready software