The availability of technologies for the generation of induced pluripotent stem cells (iPSCs) from somatic cells, such as skin and blood cells, has allowed researchers to generate limitless pools of iPSCs retaining the genetic makeup of the somatic cells from which they were derived.
Together, iPSCs and CRISPR-Cas9 systems provide researchers with effective in vitro tools for assessing gene function, disease modeling, and regenerative therapy.
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