Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder and cause of dementia worldwide. An accumulation of amyloid-β (A-β ) plaques within the brain is thought to play a central role in disease pathogenesis.
Matrix-assisted laser desportion/ionization (MALDI) mass imaging spectrometry (IMS) allows detailed visualiztion of these distinct deposits.
Download this poster to learn how:
• The distribution of A-β differs in the brains of patients with and without AD
• MALDI-IMS compares against conventional immunohistochemistry methods