Understanding Drug Efflux – Small Multidrug Resistance Family
March 18, 2021 | 10AM EST, 3PM CET
The transporters of the SMR family catalyze multidrug and toxin efflux in bacteria, energetically driven by proton influx. Not only are these proteins interesting in the context of novel antimicrobial strategies but due to their small size, they are valuable tools for a better understanding of transport mechanisms and substrate specificity.
The transporters of the SMR family catalyze multidrug and toxin efflux in bacteria, energetically driven by proton influx. Not only are these proteins interesting in the context of novel antimicrobial strategies but due to their small size, they are valuable tools for a better understanding of transport mechanisms and substrate specificity.
In the first session of the transporter webinar series, we have the opportunity to learn from two experts in the field, Randy Stockbridge and Katherine Henzler-Wildman, about their approaches and insights working with this transporter family.
Register now to learn more about:
The mechanism and function of ion-coupled transporters
Using an SSME-based assay for assessing transport stoichiometry
How to facilitate future mechanistic and functional studies of ion-coupled transporters
Speaker Information:
Dr Randy Stockbridge Assistant Professor, University of Michigan
Dr Katherine Henzler-Wildman Professor, University of Wisconsin-Madison
